Louann Brizendine is a neuro-psychiatrist and the author of "The Female Brain." She tells Jim Fleming that male brains are fueled by testosterone and female brains are fueled by estrogen and that they are chemically and physically different from each other.

And, Alan Wallace is an ex-Buddhist monk who runs the Santa Barbara Institute for Consciousness Studies, and is the author of "Contemplative Science." He tells Steve Paulson that the long tradition of rigorous investigation of the mind undertaken by Buddhism has a lot to teach Western science.

Finally, Daniel Tammet is an autistic savant and the author of "Born on a Blue Day." He loves numbers, can do calculations in his head into the millions, and can recite pi to more than 22,000 digits. But he has trouble telling right from left and looking people in the eye. Tennet talks with Anne Strainchamps about life on the autistic spectrum and how he sees numbers.

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"To the Best of Our Knowledge" is an audio magazine of ideas - two hours of smart, entertaining radio for people with curious minds. More "To the Best of Our Knowledge"

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