In Cairo, there were clashes Thursday between protesters and police blocking access to the US Embassy.
The Egyptian government has vowed to protect the embassy, following the killing of the US ambassador in Libya.
Egyptian journalist Shahira Amin is a former deputy head and senior anchor at Egypt's state-owned Nile TV.
She resigned from the position in February last year because she disapproved of the channel's coverage of the revolution.
She tells anchor Marco Werman she sees reactions in Middle East as a bigger insult to Islam than the actual film, and anti-American attacks as a strike against the Arab Spring and the revolution.